IEEE

Optimizing Enzyme-Constrained Metabolic Models by an Indicator Guided Bi-Surrogate Adaptive Multimodal Multiobjective Optimization Algorithm

Abstract: Optimization of the enzyme turnover rate kcat in enzyme-constrained metabolic models, such as S. cerevisiae’s ecYeastGEM, is essential to improve the accuracy of cellular metabolism ...
IEEE

Actuarial Risk Assessment and Pricing Optimization Algorithm Based on Graph Neural Network

Abstract: In this study, we proposed a new method combining graph sampling aggregation network (GraphSAGE), Contrastive Learning (CL) and Bayesian Optimization. First, GraphSAGE was used to model the ...