Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical ...

Researchers have demonstrated that consumer-grade 3D printers and inexpensive materials can produce advanced optical ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

A collection of protocols covering a variety of methods to achieve super resolution in microscopy to include structured illumination, single-molecule fluorescence and localization-based approaches.

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Top: Random Illumination Microscopy (RIM) utilizes random speckle patterns to achieve super-resolution imaging of biological tissues, improving resolution by a factor of two compared to the optical ...

The University of Wyoming will soon house one of the most advanced microscopes in the Mountain West, thanks to a nearly $1.3 million grant from the National Science Foundation (NSF) awarded to Eunsook ...

These developments steered the way into the field of super-resolution microscopy. This novel area has already had such a long-lasting influence on the community that two of its procedures were the ...

Current calibration methods rely on artificially constructed DNA structures or specific cellular features, each with significant drawbacks. DNA-based rulers require complex chemical synthesis and only ...