Matching excipients to API properties is essential. Hot-melt extrusion (HME) enables formation of amorphous solid dispersions (ASDs) of crystalline compounds, trapping the molecules in less-stable ...

High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...

Polyphenols have recently gained attention owing to their beneficial effects, which include antioxidant and anti-inflammatory effects. A prominent example comes from Quercetin (Que), a polyphenol that ...

Dry-powder cell-culture media (CCM) offer many advantages with respect to shipping and storage due to their reduced volume and increased stability. However, such media need to be highly soluble and ...