A dosage formula has been derived from a retrospective analysis of carboplatin pharmacokinetics in 18 patients with pretreatment glomerular filtration rates (GFR) in the range of 33 to 136 mL/min.
Body surface area-dosing does not account for the complex processes of cytotoxic drug elimination. This leads to an unpredictable variation in effect. Overdosing is easily recognised but it is ...
Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy. The BSA-based method of dose calculation was adopted without adequate investigation of its ...
Sample slices from a CT image dataset (top row), along with the corresponding masks for the automatically segmented organs used to generate patient-specific anatomy models. (Courtesy: Phys. Med. Biol.
Dose conversion: A deep learning model predicts the Monte Carlo (MC) dose distribution from the pencil beam (PB) dose, for a prostate cancer case. (a) PB dose distribution; (b) converted dose ...