We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. After being described in 2018, this molecule took our team on a six-year journey ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 nucleotides longer than typical RNAs and are widely expressed in cells, could serve ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

Profiling noncoding repetitive RNA sequences improves the sensitivity of liquid biopsy diagnostic tests for early stage cancers. As cancer is most treatable in its early stages, developing diagnostic ...

In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has been elucidated, offering new insights into potential therapeutic targets.

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

Researchers from the University of Texas and University of Tennessee set out to determine if the long noncoding RNA (lncRNA) MALAT1 (metastasis associated lung adenocarcinoma transcript 1), which is ...

Various sayings equate going fast with going alone. But none of them apply to the gene expression journey described by a research team from the University of Göttingen. The team, led by Heike Krebber, ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...