It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage ...

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

A serendipitous discovery in the lab has the potential to revolutionize embryo models and targeted drug therapies. Materials scientists at UNSW Sydney have shown that human pluripotent stem cells in a ...

An unexpected link has been found between the metabolic pathways that produce energy for embryo growth, and the cellular signalling systems that regulate cell specialization and movement during early ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a “black box” of human development. This is because human embryos are ...

Roger Sturmey receives research funding from UKRI, NC3Rs, Tommys, ESHRE, and British Heart Foundation. He serves as Chair of the Guideline Working Group for the "Governing Stem Cell-Based Embryo ...