Preclinical model systems are invaluable tools for drug discovery and development. But many complex diseases, such as nonalcoholic steatohepatitis (NASH), are difficult to recapitulate in the ...

In research, the results of studies must be precise and reproducible. Behavioral scientists have been able to demonstrate that a new experimental design can improve the reproducibility and validity of ...

The landscape of gene editing applications is expanding quickly. More and more, researchers are faced with choosing the right tools and protocols for genome engineering, including overexpressing ...

In this module, we will introduce the basic conceptual framework for experimental design and define the models that will allow us to answer meaningful questions about the differences between group ...

Statistically designed experiments have proven to be one of the few reliable, effective weapons in the 20th century arsenal of globally competitive firms. Although lacking the ephemeral "flavor of the ...