Macrolide antibiotics like azithromycin rely on a complex ring structure that’s powerful but notoriously hard to control.

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely ...

Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation.

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...

The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

A research team at Leibniz-HKI has described a new enzyme that renders the highly toxic molecule malleicyprol harmless. Malleicyprol is considered an important virulence factor of Burkholderia ...